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Gestational trophoblastic disease

The information on this page was reviewed and approved by
Maurie Markman, MD, President, Medicine & Science at CTCA.

This page was updated on July 14, 2021.

Gestational trophoblastic disease is rare. Know your options.

In a normal pregnancy, cells grow and surround the fertilized egg, connecting the egg to the wall of the uterus and forming the placenta, which is responsible for feeding the fetus during pregnancy. Gestational trophoblastic disease (GTD) is a rare condition—accounting for fewer than 1 percent of all gynecologic cancers and occurring in about one of every 1,000 in the United States. This condition develops after conception, when trophoblast cells change and form a mass in the placenta, preventing the development of a healthy fetus.

Although GTD is usually not cancerous, some tumors may become cancerous and spread. GTD is treatable, especially if caught early.

What you should know after a cancer diagnosis

Treatment options

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Several treatments may be recommended for GTD, depending on each individual patient’s unique diagnosis and circumstance. GTD treatments may include:

Surgical procedures are the first treatment option for molar pregnancies, (when a tumor develops in the uterus as a result of a nonviable pregnancy) which account for most cases of GTD.

This treatment be used alone, or in combination with surgery. It’s commonly used to treat molar pregnancies.

Learn more about treatment options for GTD

Supportive care

Surgical and chemotherapy treatments for GTD may cause a number of side effects that affect your quality of life, including pain, malnutrition and depression. Our multidisciplinary care team works with each patient to help manage the side effects of cancer and its treatment. Services recommended for GTD patients may include:


Behavioral health

​Our behavioral health support program is designed to support you and your caregivers before, during and after cancer treatment.


​Pain management

Pain management is a branch of medicine focused on reducing pain and improving quality of life through an integrative approach to care.


​Nutritional support

Every patient has the option of meeting with a registered dietitian.

Anne Strayham

Anne S.

Uterine Cancer

"The care I received at CTCA still amazes me. I felt genuine concern and empathy. If I was having a meltdown moment, someone was there to hand me a tissue. No one made me feel silly about the questions I had, and my questions were answered. At CTCA, I felt like my doctor cared, and that he takes the time to care. I don’t see him or the members of my care team checking their watches during an appointment with me. That alone is extraordinary to me."


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